Most common CNS disturbances reported with levofloxacin include headache, dizziness and drowsiness, usually occur on Day 1 and resolve after discontinuation. •. Less commonly reported CNS events include increased intracranial pressure and CNS stimulation which may lead to tremors, restlessness, anxiety. I have long had severe reservations about quinolone antibiotics, like Levaquin and Cipro. I have had these concerns since I conducted clinical trials to test new antibiotics (including a variety of quinolones) before they went to market. Now I have further concerns about them because of their overuse as an [.
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The case of an year-old man who presented to the emergency department with levofloxacin therapy–induced, acute-onset psychosis. Commonly seen adverse reactions include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion). These reactions can occur within hours to weeks after starting Levaquin. Patients of any age.
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