Administration (FDA) has approved ABILIFY MAINTENA™ (aripiprazole) for extended- release injectable suspension, an intramuscular (IM) depot formulation indicated for the treatment of schizophrenia. ABILIFY MAINTENA is the first dopamine D2 partial agonist approved as a once- monthly injection. Neuroleptic Malignant Syndrome (NMS): NMS is a potentially fatal symptom complex reported in association with administration of antipsychotic drugs including ABILIFY MAINTENA. Clinical signs of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability. Additional signs may.
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Instruct patients to avoid operating hazardous machinery, including automobiles, until they are certain ABILIFY MAINTENA does not affect them adversely. Please see FULL PRESCRIBING INFORMATION, including BOXED WARNING. References: 1. Managed Markets Insights & Technology Advanced Research. January. aripiprazole (10 mg to 20 mg) or current oral antipsychotic (). • Dosage adjustments are required for missed doses (). • Known CYP2D6 poor metabolizers: Recommended starting and maintenance dose is mg administered monthly as a single injection. (). • ABILIFY MAINTENA comes in two types of cawf.infog: technology.
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